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年轻的法克斯坦博士神推鬼撞下来到祖父的城堡，无意中发现了一本祖父的记事簿，在驼背人伊哥与性感野性的伊加帮助下，加上偷回来的脑，根据祖父的科学实验资料，成功制造了一具怪物–科学怪人。可惜，偷回来的脑出了岔子，导致科学怪人极渴望被爱，它离家出走，在郊外遇上小女孩与一名瞎子…… 影史上数一数二爆笑到极点的电影！请务必先看过1931年的《科学怪人》及1935年的《科学怪人的新娘》电影版本再来看本片，因为本片所有镜头、对白、桥段、造型等，皆和旧版作了对比，却大大颠覆成搞笑版本！。Growing up in a small town, Charlie, Alex and Nick weren't the most popular kids around after they formed "The Elite Monster Unit". Chasing notorious, mythical legends and ghosts was exciting to them, not "cool" to the other kids around. So they lived their lives on the outside of the "in" crowd. Making matters worse was Charlie's obvious crush on Brandy, one of the most popular kids in school and sister to one of the biggest bullies around. Trying to impress Brandy, Charlie accepts a dare from her brother Nick that says he and his friends must spend Halloween night in a house long rumored to be haunted.What seems to be an easy challenge quickly turns out to be a night of frights as Charlie, Nick and Alex find themselves in the fight of their lives trying to out smart (and outrun) their new nemesis, a ghost dog named Salty, who does whatever he can to make this the worst night of their lives...。68岁女导演劳瑞·安德森以对一只狗的情怀，引申出人生中的许多其他故事，911后时代的恐惧心理，美国政府的全民监听，淹死的弟弟，与母亲的心结，怀念丈夫，生与死......意识流画面，片段式影像，文艺范儿的思绪，灵动的音乐，一部极具个人隐私的抒发。。